急性链球菌感染后肾炎患儿的临床分析

Clinical characteristics of nephritis children with acute Streptococcusinfection

目的探讨和分析急性链球菌感染后肾炎患儿的临床特点及诊治情况,为后期疾病的诊治提供依据。方法选取2010年6月-2012年11月医院收治的98例急性链球菌感染后肾炎患儿为研究对象,按患儿蛋白尿程度分为A组(非大量蛋白尿)和B组(大量蛋白尿),各49例,分析两组患儿的临床特点和治疗情况。结果 A组高血压、肉眼血尿、水肿及少尿比例明显低于B组,差异有统计学意义(P<0.05);两组患儿治愈率均为100.00%;A组47例患儿蛋白尿完全恢复正常,B组45例患儿蛋白尿完全恢复正常,两组比较差异无统计学意义;症状消失平均时间A组为(16.82±3.13)d、B组为(25.22±5.73)d,两组比较差异有统计学意义(P<0.05)。结论急性链球菌感染后肾炎患儿经过对症治疗后均能达到较好预后,但大量蛋白尿患儿恢复时间较非大量蛋白尿患儿长。

OBJECTIVE To investigate and analyze the clinical features and diagnose and treatment situation of acute streptococcus infection for children in nephritis so as to provide clinical evidence for diagnose and treatment in the future. METHODS A total of 98 cases of children in nephritis with acute streptococcal infection in our hospital from Jun. 2010 to Nov. 2012 were selected as study objects. According to the degree of proteinuria, they were divided in- to group A, 49 cases （non-heavy proteinuria）, group B, 49 cases （heavy proteinuria）, and the clinical features and treatment situation in two groups of children were analyzed. RESULTS Hypertension, gross hematuria, edema and oliguria in group A was significantly lower than group B with significant difference （P〈0.05）; Cure rates in both group were 100.00%. A group of 47 cases of children with proteinuria were completely back to normal, while 45 cases in group B and the difference had no statistical significance; the mean time for symptoms disappear in group A was （16. 82 ±3.13）d, which was significantly shorter than B group （25. 22±5.73）d, （P 〈0.05）. CONCLUSION Acute streptococcus infection for children in nephritis can achieve better outcomes by symptomatic treatment, but children with heavy proteinuria has longer recovery time than non-heavy proteinuria in children.