摘要
肥胖不仅指过多的脂肪积聚,还包括脂肪的分布异常。内脏脂肪的增加是多种代谢性疾病(如2型糖尿病、心血管疾病等)的高危因素。脂肪组织通过分泌脂肪细胞因子和炎症因子调节胰岛素敏感性和参与胰岛素信号通路。因此,研究脂肪组织分布与内分泌特点对防治肥胖及其相关疾病具有重要的意义。
Obesity, not only defined as excessive fat accumulation, but also implies abnormal fat distribution. The increasing visceral adipose tissue is a risk factor for multiple metabolic diseases, such as Type 2 diabetes and cardiovascular disease. Adipose tissue regulates the sensitivity of insulin and insulin signal pathway by secretion of various adipokines and inflammatory factors. Therefore, endocrine is of great significant in prevention and study of adipose tissue distribution and the characteristics of treatment of obesity and related diseases.
出处
《国际病理科学与临床杂志》
CAS
2013年第6期544-547,共4页
Journal of International Pathology and Clinical Medicine
基金
国家自然科学基金(81070667
81270925)
湖南省自然科学基金重点项目(12JJ2050)~~
关键词
皮下脂肪组织
内脏脂肪组织
脂肪分布
胰岛素抵抗
subcutaneous adipose tissue
visceral adipose tissue
adipose depots
insulin resistance