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右美托咪定对老年前列腺电切术患者小剂量布比卡因腰麻的影响 被引量:2

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摘要 目的评价静脉应用右美托咪定对老年患者小剂量布比卡因腰麻阻滞时间的影响。方法 51例择期行前列腺电切术老年患者(〉65岁,ASAⅠ~Ⅱ级),随机分为右美托咪定组(DMT组,n=26)和对照组(n=25),分别于小剂量布比卡因(6 mg)腰麻实施前静注1.0μg/kg的右美托咪定和10 ml的生理盐水。术中监测平均动脉压(MAP)、脉搏血氧饱和度(SpO2)、心率(HR),观察运动和感觉阻滞程度及不良反应,并进行术中镇定和术后镇痛评分。结果 DMT组感觉阻滞及运动阻滞持续消退时间明显长于对照组,同时术中镇定评分明显高于对照组;DMT组术中最低MAP及最低HR明显低于对照组,其阿托品应用率明显高于对照组;对照组术后镇痛评分明显高于DMT组,且DMT组在恢复室观察时间较长,其他不良反应无差异。结论静脉应用1.0μg/kg的右美托咪定能显著延长老年前列腺切除术患者小剂量腰麻阻滞的时间,提供更完善的术后镇痛,但可能引发术中镇定过度、心动过缓。
出处 《中华临床医师杂志(电子版)》 CAS 2013年第20期125-127,共3页 Chinese Journal of Clinicians(Electronic Edition)
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