高压氧治疗对小儿外伤性急性弥漫性脑肿胀预后的影响

Effects of Hyperbaric Oxygen Treatment on Prognosis of Children with Posttraumatic Acute Diffuse Brain Swelling

目的 探讨高压氧治疗对小儿外伤性急性弥漫性脑肿胀预后的影响.方法 回顾性分析2000年1月～2013年1月56例外伤性急性弥漫性脑肿胀患儿的临床资料.其中31例行高压氧治疗,25例未行高压氧治疗,比较两组患儿的觉醒时间及疗效.结果 高压氧组觉醒时间为13.2±4.3天,明显优于无高压氧组（17.8±5.5天,P〈0.05）,高压氧组预后良好率为77.4%,明显优于无高压氧组（48.0%,P〈0.05）,重残及死亡率为22.6%,低于无高压氧组（52.0%,P〈0.05）.结论 在常规治疗基础上结合高压氧治疗,能够显著提高小儿外伤性急性弥漫性脑肿胀的疗效,改善生存质量.

Objective To investigate the effect of Hyperbaric oxygen（HBO） on prognosis of children with posttrau- marie acute diffuse brain swelling（PADBS）. Methods The date of PADBS admitted between January 2000 and January 2013 were analyzed. Among 31 patients who received HBO treatment were taken as study group,and 25 patients who re- ceived non HBO treatment were taken as control group. The awakening time and prognosis were compared between two groups. Result The awakening time in study group was 13.2 ± 4.3 d, which was significantly better than that in control group （ 17. 8 ± 5.5 d, P 〈 0. 05 ）. The rate of favorable prognosis in study group was 22.6%, which was significantly better than that in control group（48. 0%, P 〈 0.05 ）. Disability rate and mortality were lower compared with the control group （52.0% ,P 〈 0.05 ）. Conclusion Integrated therapy combined with HBO for PADBS in children may promote signifi- cantly both the therapeutic effectiveness and the survival quality.