原发性肾平滑肌肉瘤回顾分析

Retrospective study of primary renal leiomyosarcoma

目的 探讨原发性肾平滑肌肉瘤的疾病特点及治疗要点.方法 回顾分析1998年至2012年间7例原发性肾平滑肌肉瘤的诊治经过,并随访观察疾病的进展及转归,并对其进行生存分析.结果 7例患者全部接受手术治疗,同时部分接受了辅助治疗,患者中位生存期为11.0（2.7~19.2）个月;术后1年生存率为28.5%.结论 肾平滑肌肉瘤是一种少见的肾脏恶性肿瘤,其恶性程度较高,预后不良,早期手术是治疗的关键.

Objective To explore the characteristics and treatment of primary renal leiomyosarcoma. Methods We retrospectively ana- lyzed the treatment of 7 cases of primary leiomyosarcoma of kidney from 1998 to 2012, and made follow-up observation of disease progres- sion and prognosis, and carried out survival analysis. Results All 7 patients received operation, and adjuvant therapy. The median sur- vival period was 11 months （2.7 - 19.2）. After 1 year survival rate was 28.5%. Conclusions Leiomyosarcoma of kidney is a rare re- nal malignant tumor, with high tumor malignant degree and poor prognosis. Early operation is the key to treatment.