精神科糖尿病住院患者医院感染的临床特点

Research of nosocomial infections on diabetes mellitus patients in psychiatic department

目的探讨精神科糖尿病住院患者医院感染的临床特点。方法选择我科2009-06—2012-06住院治疗的320例糖尿病合并精神疾病患者为研究对象,探讨医院感染的发生率、感染部位、医院感染相关因素及病原菌分布。结果 320例患者中共42例患者发生医院感染,发生率13.1%;感染部位分布构成比以呼吸系统为首位,占40.5%(17例),其次为胃肠道、皮肤软组织及泌尿系统(23.8%、11.9%和9.5%)。Logistic分析结果显示:性别、年龄、病程、血糖控制情况及住院时间是糖尿病合并精神疾病患者发生医院感染的影响因素(P<0.05);42例患者病原菌阳性率为61.9%(26株),其中革兰阴性杆菌占57.7%(15株),革兰阳性菌占30.8%(8株),真菌11.5%(3株)。结论糖尿病合并精神疾病患者医院感染发生率高,临床工作中应针对相关因素进行干预,减少医院感染的发生。

Objective To explore the clinical feature of nosocomial infections of diabetes mellitus patients in sychiatric department. Methods Totally 320 cases with diabetes mellitus complicated with mental disorder from June 2009 to June 2012 were selected as research subjects. The occurrence of nosoeomial infections, infection sites, correlative factors and species of pathogenic bacteria were studied. Results Nosocomial infections occurred in 42 patients （13.1%） among 320 patients, including 40.5% cases of respiratory system, 23.8% cases of gastrointestinal tract, 11.9% cases of skin and soft tissue infections and 9.5% cases of urinary system. Logistic analytic result showed that sex, age, course of disease, blood sugar and hospital stay were the influencing factors for nosoeomial infections. Totally 26 specimens （61.9 %） were cultured positive, mainly with Gram-Negative bacillus （57.7%）, Gram-positive bacteria （30.8%） and fungus （11.5%）. Conclusion High incidence of noso-comial infections occurred in diabetes mellitus complicated with mental disorder. Intervention measures should made according to the interfered factors in order to decrease nosocomial infections.