基于席夫碱结构的香豆素类荧光探针的合成及性能研究

Synthesis and Properties of Coumarin Fluorescent Probe Based on Schiff-base

以3-甲酰基-7-二乙胺基香豆素和2-氨基烟酸为原料，合成了一种席夫碱结构的香豆素类荧光探针，该合成方法简单，收率较高，产物易提纯。研究结果表明，当往探针中加入Cu2＋时，探针的荧光强度急剧升高，而加入其他金属离子时，探针的荧光强度变化较小，Cu2＋浓度在0—5．0×10^-4mol／L范围内，探针的荧光强度随着Cu^2＋溶度的增大而增强。

A novel eoumarin fluorescent probe was synthesized based on 3-methyl acyl-7-diethylamine coumarin and 2-amino-nicotinic. The productivity was high and the product was easily to be purified. It was found that the compound had high fluorescence selectivity for Cu2＋. When the concentration of Cu2＋ was in the range of 0 -5.0 × 10-4 mol/L,the fluores- cence of the compound was enhanced along with the concentration of Cu2＋ increased.