摘要
目的探讨不同胆红素浓度对血浆凝血酶原时间(PT)与活化部分凝血活酶时间(APTT)检测结果的影响,进而得出校正公式。方法对不同TBIL浓度的质控血浆进行血浆PT和APTT的测定,并用二次回归方程得出校正公式。结果当胆红素浓度低于20μmol/L时,对血浆PT和APTT检测结果的影响差异无统计学意义(P>0.05);随着胆红素浓度的增高,PT和APTT的检测结果随之升高。结论胆红素浓度轻度增高的血浆对PT结果的影响不大,但胆红素浓度明显升高的血浆可能会对PT和APTT检测结果产生干扰。
Objective To investigate the influence of different concentrations of total bilirubin（TBIL） on the detection results of plasma prothrombin time（PT） and activated partial thromboplastin time（APTT） in order to ob- tain the corrected formula. Methods The quality control plasma with different TBIL concentrations was performed the determination of plasma PT and APTT and the quadratic regression equation was adopted to obtain the corrected formula. Results When the TBIL concentration 〈20 μmol/L,its influence on the detection results of plasma PT and APTT had no statistical significance; with the TBIL concentration increase, the detection results of plasma PT and APTT were increased. Conclusion Slightly increased plasma TBIL concentration have little influence on the PT de- tection results, but the plasma with significantly increased TBIL concentration could have interference to the plasma PT and APTT detection results.
出处
《检验医学与临床》
CAS
2014年第1期34-35,44,共3页
Laboratory Medicine and Clinic
