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卵子玻璃化冷冻在体外受精-胚胎移植取精失败周期中的应用 被引量:9

Clinical application of oocyte vitrification in failed sperm acquisition cycles of IVF-ET
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摘要 目的探讨卵子玻璃化冷冻在体外受精-胚胎移植(IVF-ET)取精失败周期中的应用。方法 2010年8月至2012年8月,在解放军第174医院生殖医学中心进行IVF-ET治疗的5例患者,取卵日因男方因素无法进行受精者,在知情同意后对部分卵子进行玻璃化冷冻保存。结果 5例患者均解冻了取卵日实施全部冷冻保存的卵子。共复苏卵子35枚,存活24枚,复苏率68.57%;有24枚MⅡ卵子行显微授精(ICSI),受精22枚,受精率91.67%;形成19枚胚胎,卵裂率86.36%,获可用有效胚胎16枚。5个移植周期移植胚胎13枚,临床妊娠2例,分娩2个健康婴儿,胚胎种植率15.38%,活产率40%。剩余3枚胚胎冷冻保存。结论卵子的玻璃化冷冻保存可以获得一定的临床妊娠率,对IVF-ET治疗中取精失败患者可作为临床治疗的一个供选择的方法。
出处 《实用医院临床杂志》 2014年第1期156-157,共2页 Practical Journal of Clinical Medicine
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参考文献8

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二级参考文献12

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