气相色谱-质谱法测定婴幼儿乳粉中16种邻苯二甲酸酯类迁移物

Determination of 16 Phthalate Esters Migrants Content in Infant Milk Powder by GC-MS

建立了一种同时测定婴幼儿乳粉中16种邻苯二甲酸酯类迁移物的气相色谱-质谱（GC-MS）检测方法。采用超纯水将婴幼儿乳粉中的邻苯二甲酸酯类物质复溶，通过正己烷提取净化后采用气相色谱一质谱选择离子检测模式（SIM）进行定量分析。当加标水平在0．2～5．0mg／kg时，16种邻苯二甲酸酯类物质均呈现良好的线性关系，相关性系数均大于0．995。回收率为75．0％～107．6％，相对标准偏差（RSD）为0．68％～6．10％。该方法操作简便、检测时间短、重现性好，适用于同时检测婴幼儿乳粉中16种邻苯二甲酸酯类物质。

A suitable GC-MS method was established for the determination of 16 phthalate estersmigrants in infant milk powder. With ultrapure water to redissolve the phthalate esters in infant milk powder, with n-hex- ane to extract and purify them,then used GC-MS to quantitative analyze them with SIM mode. 16 phthalate es- ters showed good linear relationships in concentration range of 0.2 to 5.0mg/kg ,the recoveries of phthalate es- ters added in infant milk powder ranged from 75.0% to 107.6%, the correlation coefficientswere larger than 0. 996, relative standard deviations （RSD） were 0.68% to 6.10%. This method is simple,short time spend- ing and with good reproducibility, it is suitable for the determination of 16 phthalate esters in infant milk pow- der.