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丁咯地尔联合辛伐他汀治疗早期糖尿病肾病的临床观察 被引量:5

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摘要 糖尿病肾病(DN)是糖尿病常见的慢性并发症之一.2型糖尿病患者糖尿病肾病的发生率为20%~50%{1}。选择我科2008年3月至2011年8月收治的46例早期DN患者.给予丁咯地尔联合辛伐他汀取得了良好疗效,报告如下。
出处 《北京医学》 CAS 2014年第1期69-70,共2页 Beijing Medical Journal
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  • 1蔡景英,柳亢宗,胡继军.糖尿病肾病患者血脂异常及血清脂蛋白(a)与糖尿病肾病的关系[J].临床内科杂志,2005,22(6):403-405. 被引量:19
  • 2Kwak B, Mulhaupt F, Myit S, et al. Statins as a newly recognized type of immunomodulator. Nat Med, 2000,6 ( 12 ) : 1399-1402.
  • 3Massy ZA, Kim Y, Guijarro C, et al. Low-density lipoprotein-induced expression of interleukin-6, a marker of human mesangial cell inflammation : effects of oxidation and modulation by lovastatin. Biochem Biophys Res Commun,2000,267 (2) :536-540.
  • 4Heusinger RJ, Fischer B, Goppelt SM, et al. Differential effects of simvastatin on mesangial cells. Kidney Int, 2004, 66( 1 ) : 187-195.
  • 5Bussolati B, Deregibus MC, Fonsato V, et al. Statins prevent ox-idized LDL-induced injury of glomerular podocytes by activating the phosphatidylinositol3-kinase/AKT-signaling pathway. J Am Soc Nephrol, 2005,16(7) : 1936-1947.
  • 6Vieira JM Jr, Rodrigues LT, Mantovani E, et al. Statin monotherapy attenuates renal injury in a salt-sensitive hypertension model of renal disease. Nephron Physiol, 2005, 101(4) :82-91.
  • 7Vasantha K, Lixia Z, Hui P, et al Targeting of RhoA/ ROCK signaling ameliorates progression of diabetic nephropathy independent of glucose control. Diabetes, 2008, 57 (3) :714-723.
  • 8Danesh FR, Sadeghi MM, Amro N, et al. 3-Hydroxy-3- methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial ceils via modulation of Rho GTPase p21 signaling pathway: implications for diabetic nephropathy. PNAS,2002,99(12) :8301-8305.
  • 9Singh R, Alavi N, Singh AK, et al. Role of angiotensin II in glucose- induced inhibition of mesangial matrix degradation. Diabetes, 1999,48 (10) :2066-2073.
  • 10Banes-Berceli AK, Shaw S, Ma G, et al. Effect of simvastatin on high glucose and angiotensin II-induced activation of the JAK/STAT pathway in mesangial cells. Am J Physiol Renal Physiol,2006,291 ( 1 ) :F116-F121.

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