妊娠期代谢紊乱综合征患者妊娠结局的研究

Pregnancy Outcome Study of Metabolic Disorders in Pregnancy Syndrome Patients

目的探讨妊娠期代谢紊乱综合征(GMS)患者是否存在不良妊娠结局情况。方法采取回顾性调查研究方法,针对2013年7月至10月在大连市旅顺口区人民医院产科住院分娩的孕产妇,筛选出符合妊娠期代谢紊乱综合征的孕产妇53例作为研究组(GMS组),其余孕产妇584例为对照组,调查研究组与对照组的妊娠结局情况,包括妊娠期高血压疾病子痫前期的发生情况,妊娠期糖尿病的发生率,妊娠期羊水过少、羊水过多、胎膜早破、产前出血的发生率,产时手术产率,子宫收缩乏力引起产后出血的发生率,以及巨大儿、胎儿生长受限、新生儿窒息、肺炎甚至死胎等胎儿新生儿不良结局的发生率。结果妊娠期代谢紊乱综合征对妊娠的影响是可以增加早产、羊水过少、羊水过多的发生,可以增加胚胎发育异常、胎死宫内的发生概率,产时的影响是增加手术产率,增加胎盘早剥以及宫缩乏力产后出血的发生率,对于新生儿的影响是增加巨大儿出生率,可导致胎儿生长受限而分娩低出生体质量儿。孕期体质量过度增长、异常高血脂与妊娠期代谢紊乱综合征关系密切,与不良妊娠结局存在因果关系。结论妊娠期代谢紊乱综合征是一种对孕母及胎儿均有严重不良影响的疾病,加强孕期监护及保健,控制体质量、合理营养、及早发现、治疗GMS对于减少孕产期并发症,避免不良妊娠结局具有重要的临床意义。

Objective On patients with pregnancy metabolic disorder syndrome （GMS） whether there is any adverse pregnancy outcomes. Methods Adopts the method of.retrospective study, select 53 cases of women in pregnancy who confirmed as pregnancy metabolic disorder syndrome to be the experimental group, during the period of July 2013 to October 2（}13 in dalian Nshunkou district people＇s hospital. And the rest 594 cases of pregnant women as the contro~ group. Survey experimental group and the control group of pregnancy outcomes, including of preeclampsia, gestational hypertension disease, the incidence of gestational diabetes, gestational oligohydramnios, hydramnios, premature rupture of membranes, the incidence of antepartum haemorrhage, intrapartum surgery yields, caused the incidence of postpartum hemorrhage, uterine contractions fatigue and macrosomia, fetal growth restriction, neonatal asphyxia, pneumonia, and even stillbirth etc. The incidence of fetal neonatal adverse outcomes. Results The impact of metabolic disorder syndrome during pregnancy is that it can increase the occurrence of premature birth, oligohydramnios, hydramnios, it can increase the risk of abnormal embryonic development, fetal intrauterine, intrapartum impact is to increase the rate of cesarean delivery, increase of placental abruption and contractions fatigue, the incidence of postpartum hemorrhage for newborn is to increase the influence of macrosomia birthrate, which can lead to fetal growth restriction and childbirth low birth weight. Excessive growth, abnormal pregnancy weight hyperlipidemia and closely related to metabolic disorder syndrome during pregnancy, causal relationship and adverse pregnancy outcomes. Conclusion Metabolic disorder syndrome during pregnancy is diseases that have serious adverse effects to both mother and fetus, strengthen monitoring and health care during pregnancy, weight control, reasonable nutrition, early detection and treatment of GMS is very significant for reducing maternal complications and avoiding adverse pregnancy outcomes.