背向散射积分超声组织定征对梗塞心肌的定量评价

Quantitative Evaluation of Infarcted Myocardium by Ultrasonic Tissue Chracterization With Integrated Backscatter

目的 :探讨背向散射积分检测技术定量评价梗塞心肌组织特征的临床价值。方法 :检测 77例急性期、陈旧期心肌梗塞患者的梗塞心肌及 2 0例对照者的正常心肌背向散射积分标化值 (IBS% ) ,背向散射积分周期变异幅度 (CVIB)及其标化值 (CVIB% ) ,标化背向散射积分周期延迟时间 (DTCV% )以及收缩期室壁增厚率 (Δ T% ) ,并比较不同梗塞时间 IBS参数的变化。结果 :梗塞心肌的 CVIB及 CVIB%明显低于正常心肌 ,IBS%及 DTCV%则明显增高。梗塞时间延长 ,IBS%亦随之增高 (陈旧期组 73.87± 13.46 ,急性期组 5 9.5 0± 9.35 )。CVIB及 CVIB%均与Δ T%呈高度相关 (r =0 .746 ,0 .75 6 ,P <0 .0 1) ,IBS%及 DTCV%与 ΔT%亦具有一定的相关性 (r =0 .746 ,0 .75 6 ,P <0 .0 1)。结论 :背向散射积分检测技术能够定量检测梗塞心肌的组织特征 ,有助于评价心肌的收缩能力及心肌纤维化程度。

Objective: Our purpose was to determine the use of ultrasonic tissue characterization with integrated backscatter in evaluation of infarcted myocardium. Methods: Some parameters were measured in 77 patients with recent or old anteroseptal myocardial infarction and 20 healthy persons. They are calibrated myocardial integrated backscatter (IBS%), magnitude of cyclic variation in integrated backscatter(CVIB) and its calibration (CVIB%), calibration of delayed time of CVIB (DTCV%) and systolic wall thickening (ΔT%).The parameters IBS of infarcted myocardium at different time were compared. Results: The CVIB and CVIB% of infarcted myocardium were lower and, IBS% and DTCV% were higher than those of normal myocardium. The IBS% increased with the going of infarcted time. The IBS parameters were related with ΔT%. Conclusion: Analysis of integrated backscatter parameters using Acoustic Densitometry can quantitatively assess the degree of myocardial fibrosis and systolic ability.