肝胃百合汤治疗功能性消化不良肝胃不和证患者的临床观察及对CCK的影响

Impact on CCK and clinical observation on treating functional dyspepsia disharmony of Ganwei Buhe syndrome with the Ganwei Baihe decoction

目的:观察名老中医夏度衡经验方之肝胃百合汤治疗功能性消化不良肝胃不和证的临床疗效及对CCK的影响。方法:将60例功能性消化不良肝胃不和证门诊患者随机分为两组,治疗组30例,给予肝胃百合汤治疗;对照组30例,给予依托必利片治疗,两组均以治疗30d为1个疗程,观察两组临床疗效及血液中CCK的变化。结果:治疗组中医证侯疗效优于对照组(P<0.05),两组皆能降低血液中CCK水平,治疗组较对照组更明显(P<0.01)。结论:肝胃百合汤是治疗功能性消化不良肝胃不和型的有效方药,能明显改善患者的临床症状,其机制可能是通过降低血液中CCK(Cholecystokinin,胆囊收缩素)的含量。

Objective： To observe the clinical effect on treating functional dyspepsia disharmony of Ganwei Buhe syndrome with the Ganwei Baihe decoction and impact on CCK. Methods： 60 patients with functional dyspepsia disharmony of Ganwei Buhe syndrome were randomly divided into two groups. The treated group, 30 patients received the Ganwei Baihe decoction treatment; 30 patients of control group received treatment Itopride tablets. 30 days for a course in two groups. To observe the clinical efficacy and changes of CCK in blood. Results： The efficacy of the treated group was better than the control group （P〈0.05）. The two groups can lower blood levels of CCK. The treated group was significantly better than the control group （P〈0.01）. Conclusion： Ganwei Baihe decoction is an efficient prescription of functional dyspepsia disharmony of Ganwei Buhe syndrome, can significantly improve the clinical symptoms, the mechanism may be lowering blood CCK （Cholecystokinin, CCK） content.