回药扎里奴思方对急性脑梗死患者神经功能评分的影响

Effects of Zhali Nusi Fang on Neurological Function Changes in Patients with Acute Cerebral Infarction

目的:观察扎里奴思方对急性脑梗死患者神经功能评分的影响及其临床疗效的评估。方法:将84例脑梗死患者按随机数字表法随机分为试验组和对照组,内科基础治疗相同,试验组42例采用扎里奴思方,对照组42例应用尼莫地平片,疗程28 d。比较治疗前后患者临床疗效,神经功能缺损评分及日常生活能力指数的变化。结果:两组病例于治疗7,14,28d后进行比较,试验组及对照组治疗前后比较差异有显著性(P<0.05),但试验组显效率明显优于对照组(P<0.05)。试验组总有效率88.09%,对照组69.05%,两组比较差异有显著性;神经功能缺损评分及日常生活能力指数两组均有不同程度改善,以治疗组7,14 d作用尤为明显(P<0.05)。结论:脑卒中患者给予扎里奴思方能够促进缺损神经功能的恢复,改善脑梗死后遗活动不利及日常生活能力的下降,是治疗急性脑梗死临床安全有效,值得推广应用的药物。

Objective： To know the effects of Zhali Nusi fang（ZLNSF） on the Neurological function changes and its clinical efficacy assessment in patients with acute cerebral infarction. Method： Eighty-four patients with cerebral infarction were randomly divided into treatment group （42 patients）and control group（42 patients）;the treatment group were given ZLNSF, the control group were treated with nimodipine tablets;all groups in the same basic treatment and time. The clinical efficacy,neurologic impairment scores and daily living ability index changes were observed before and after treatment. Result： The two groups were compared in the treatment of 1,7,14,28 days;the treatment group before and after treatment,the differences were significant （P 〈 0.05）,while the treatment group was significantly better than the control group （P〈0.05）. Compared with the control group,the clinical efficacy of the treatment group were significant increased （P 〈 0.05）.The treatment group total effective rate was 88.09%, 69.05% of the control group, the difference was significant;neurological deficit scores and activities of daily living index in both groups improved to some extent, particularly evident 1-14 days role in the treatment group （P〈0.05）. Conclusion： ZLNSF can promote the recovery of defects nerve function, improve the cerebral infarction after math of adverse events and activities of daily living decline, ZLNSF is a clinically safe and effective treatment of acute cerebral infarction, that should be widely applied.