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吉西他滨联合顺铂治疗晚期乳腺癌内脏转移的疗效观察 被引量:3

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摘要 目的探讨吉西他滨联合顺铂治疗晚期乳腺癌的近期疗效和不良反应。方法选择51例已用紫杉类和(或)葸环类化疗后出现内脏转移的晚期乳腺癌患者。采用吉西他滨:1000mg/mz,静脉滴注,第1、8天;顺铂:25mg/m2,静脉滴注,第1~3天,21d为1个周期,至少2周期后评价疗效。结果CR4例(7.8%),PR21例(41.2%),SD15例(29.4%),PD11例(21.6%),总有效率为45.1%。中位生存期12.5个月,中位疾病进展时间5.8个月。主要不良反应为骨髓抑制及胃肠道反应。结论吉西他滨联合顺铂治疗晚期乳腺癌具有较好的近期疗效,不良反应可耐受,是有效的解救方案。
作者 谭晶波 刘艳
出处 《中国医药指南》 2014年第3期76-77,共2页 Guide of China Medicine
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