卵巢卵黄囊瘤临床病理分析

Clinicopathological analysis of ovarian yolk sac tumor

目的观察与研讨卵巢卵黄囊瘤（YST）患者临床病理、诊治方式及预后情况。方法回顾分析两院1998～2012年收治的41例卵巢YST患者临床资料。结果典型与混合型病例临床比例均明显高于其他类型（P〈0．05），典型与混合型病例比例差异无统计学意义（P〉0．05）；术后随访发现：临床处于I期与Ⅱ期患者均健在的有13、10例；2例均为混合型I期患者手术3年后死亡；3例临床处于Ⅱ期患者手术2年后死亡，其中有2例为混合型；临床8例Ⅲ期患者术后仅存活1年为2例，其余6例存活未超过2年；临床Ⅳ期5例患者术后存活均未超过3个月。结论临床多取材并进行全面观测的方式有利于对卵巢YST的确诊，手术治疗与化疗结合可提升患者的存活率。

Objective To observe and discuss the ovarian yolk sac tumor （YST） clinical pathology, diagnosis and treatment methods and prognosis. Methods Retrospective analysis of clinical data of patients with ovarian YST in our hospital. Results The typical clinical cases with mixed ratio were significantly higher than other types （P 〈 0. 05 ）, the typical proportion of cases with mixed significant difference （ P 〉 0. 05 ） ; postoperative follow-up found that： in clinical stage I and II patients were there 13,10 patients alive; 2 cases were mixed stage I patients died after surgery three years; 3 cases in stage I1 clinical surgery two years after the death of patients, including two cases of mixed type ; clinical 8 stage I1 patients after only two cases sur- vived one year, and the remaining six cases survived less than 2 years; clinical 5 stage 1V were patients survived for more than three months. Conclusion The clinical observations and more comprehensive coverage and the way is beneficial for the diagnosis of ovarian YST, surgery combined with chemotherapy can improve the pa- tient＇ s survival.