EV71所致重症手足口病78例临床分析

Clinical analysis of 78 cases of severe hand-foot-mouth disease caused by enterovirus 71 infection

目的探讨肠道病毒71型（EV71）所致的重症手足口病（HFMD）患儿的临床特点及治疗转归。方法对2010年3月-2012年11月收入院的78例EV71所致的重症手足口痛患儿的临床表现，实验室检查及治疗与转归资料进行分析。结果78例患儿治愈69例（88．46％），治疗无效6例（7．69％），3例（3．85％）患儿留有单侧下肢迟缓性麻痹。结论EV71感染可累及多系统多器官，早期发现危重征象，早期治疗多数预后良好。

Objective To explore the children with severe hand- foot -mouth disease caused by EV71 clinical char- acteristics and outcome of treatment. Methods Clinical data of hospital children with severe hand, foot and mouth dis- ease caused by EV71 infection from march 2010 to November 2012 were analyzed retrospectively. Results 88.46%pa- tients were cured,6 ease （7.69 %） ineffective, In 3 patients （3.85 %） children with one side acute flaccid paralysis . Conclusion EV71 infection make multiple system organ involved, the early detection of critical signs, early treatment, most diseases is good prognosis.