血清孕酮、人绒毛膜促性腺激素及雌二醇联合检测在孕6~8周先兆流产中的临床意义

Serum progesterone, human chorionic gonadotropin and estradiol joint detection in pregnancy 6~8 Zhou Xianzhao abortion clinical significance

目的探讨血清孕酮、人绒毛膜促性腺激素及雌二醇联合监测在早孕期先兆流产中的临床意义。方法选取孕龄在6~8周的早期妊娠孕妇共162例,根据妊娠结局将其分成3组,继续妊娠组56例,胚胎停育组36例,对照组70例。按孕周又分成3个亚组。采用化学发光免疫分析仪检测血清孕酮（P）、人绒毛膜促性腺激素（HCG）及雌二醇（E2）水平。结果孕6~8周血清孕酮（P）、人绒毛膜促性腺激素（HCG）及雌二醇（E2）水平继续妊娠组低于对照组,胚胎停育组低于继续妊娠（P〈0.05）,差异有统计学意义。结论血清孕酮（P）、人绒毛膜促性腺激素（HCG）及雌二醇（E2）是维持早期妊娠的重要因素。可以预测先兆流产保胎治疗的预后,判断能否继续妊娠提供数据参考。

Objective To investigate the serum progesterone,human chorionic gonadotropin and estradiol joint monitoring clinical significance in early pregnancy,threatened abortion.Methods Select early gestational age in six to eight weeks of pregnancy,a total of 162 cases of pregnant women,it is divided into three groups according to the pregnancy outcome,group 56 cases continue to pregnancy,the embryo TingYu group 36 cases,control group 70 cases.According to gestational age is divided into three subgroups.Immunized with chemiluminescence analyzer to detect serum progesterone（P）,human chorionic gonadotropin（HCG） and estradiol（E2） levels.Results At six to eight weeks serum progesterone（P）,human chorionic gonadotropin（HCG） and estradiol（E2） levels continue to pregnancy group is lower than the control group,the embryo TingYu group below to continue the pregnancy（P0.05）,the difference was statistically significant.Conclusion Serum progesterone（P） and human chorionic gonadotropin（HCG） and estradiol（E2） is an important factor to maintain the early pregnancy.Can predict threatened abortion spuc treatment prognosis,judge can continue to provide the data reference pregnancy.