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组蛋白乙酰化酶和去乙酰化酶对心脏发育影响的研究进展 被引量：3

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摘要 心脏发育受遗传和环境双重影响,任何微小的病变都会导致心脏发育异常,但潜在的机制仍不清楚.心脏发育相关基因的顺序表达是构建完美心脏的生物学基础.随着分子生物学技术的发展,人们逐渐意识到环境因素对心脏发育影响的重要性.表观遗传学的提出为心脏发育异常的研究带来了新的契机.
作者 彭昌 田杰
机构地区 重庆医科大学附属儿童医院心脏内科
出处 《广东医学》 CAS CSCD 北大核心 2013年第24期3818-3820,共3页 Guangdong Medical Journal
基金 国家自然科学基金资助项目(编号:81270234) 重庆市重点实验室专项经费自主科研课题
关键词 心脏发育 组蛋白乙酰化酶 去乙酰化酶 分子生物学技术 表观遗传学 发育异常 环境因素 生物学基础
分类号 R541.1 [医药卫生—心血管疾病]
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参考文献35

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共引文献4

同被引文献23

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引证文献3

二级引证文献7

广东医学
2013年 第24期

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