普外科3种清洁手术预防用抗菌药物干预前后效果分析

To analyze the effect of prophylactic antibiotics usage for three clean surgical operations in general surgery with or without intervention

目的：对比干预前后我院普外科3种清洁手术围术期预防性应用抗菌药物的合理性,考查干预措施的实施效果。方法：选取2009年9月-2010年2月（干预前）及2011年9月-2012年2月（干预后）3种清洁手术的出院病历,对比干预前后预防性应用抗菌药物的合理性。结果：干预后抗菌药物的选择、联合用药、给药时机的合理性显著提高,但仍存在使用率较高、用药疗程过长的问题。结论：采取的抗菌药物预防性应用的干预措施具有可行性和有效性,对促进安全、合理地使用抗菌药物起到了积极促进作用,但仍有待加大力度,进一步规范化管理。

Objective： To compare the rationality of prophylactic antibiotics in three clean surgical operations with or without intervention and investigate the effect of intervention measures. Methods： The rationality of prophylactic antibiotics use in three clean surgical operations was analyzed by comparing the case history collected from Sep. 2009 to Feb. 2010（without intervention） to the case history collected from Sep. 2011 to Feb. 2012（with intervention）. Results： The rationality of prophylactic antibiotics use was improved remarkably such as the selection of antibiotics, drug combination and the opportunity of administration with intervention. There were still some problems such as high utilization rate and long course of treatment. Conclusion： The intervention measures were effective and feasible and promoted the reasonable use of prophylactic antibiotics. But it still need more attention and strengthened method to standardize the management.