速效救心丸治疗急性冠状动脉综合征的疗效观察

Observation of the Clinical Effect of Suxiao Jiuxin Pills on Patients with Acute Coronary Syndrome

目的观察氯吡格雷联合速效救心丸对急性冠状动脉综合征(ACS)患者的临床疗效。方法将2010年1月-2011年12月收治的ACS患者随机选取97例后随机分为治疗组(氯吡格雷联合速效救心丸组,48例)和对照组(氯吡格雷组,49例),以1个月为1个疗程,1个疗程后观察临床疗效、心绞痛发作频率、ST段位移的变化及不良反应的发生情况。结果 1个疗程后,治疗组总有效率为79.2%,对照组总有效率为51.0%,两组间比较差异有统计学意义(P<0.05)。两组在治疗后心绞痛发作频率、ST段位移均明显改善,与治疗前比较,差异有统计学意义(P<0.05);在治疗后,两组间比较差异有统计学意义(P<0.05),治疗组临床疗效、ST段位移变化优于对照组。结论氯吡格雷与速效救心丸联用治疗ACS比单用氯吡格雷疗效好,值得临床推广应用。

Objective To observe the clinical effect of clopidogrel combined with Suxiao Jiuxin Pills on patients with acute coronary syndrome （ACS）. Methods Ninety-seven patients with ACS diagnosed between January 2010 and December 2011 were divided into the treatment group （treated with clopidogrel combined with Suxiao Jiuxin Pills） （n=48） and the control group （treated with single clopidogrel） （n=49）. One month was regarded as a treatment course. After one month, we observed the clinical effect, heart attacks frequency, ST segment changes and adverse reactions for the patients. Results The total effective rate was 79.2% in the treatment group and was 51.0% in the control group. There was significant difference between the two groups （P 〈 0.05）. Heart attacks frequency and ST segment were reduced significantly in both the two groups after treatment （P 〈 0.05）. The curative effect in the treatment group was significantly better than that in the control group after treatment （P 〈 0.05）. Conclusion Clopidogrel combined with Suxiao Jiuxin Pills have a better clinical effect in the treatment of ACS than single clopidogrel.