含caspase募集结构域的膜相关鸟苷酸激酶1的免疫调节作用
摘要
含caspase募集结构域的膜相关鸟苷酸激酶1(CARMAl)作为膜相关的鸟苷酸激酶(MAGUK)家族成员之一,在淋巴细胞中特异性表达。近年来的研究表明,CARMAl对T、B和NK淋巴细胞的发育有重要作用,并参与固有及适应性免疫应答。此外,已证实CARMAl参与人类一些免疫性疾病的发生。
出处
《国际输血及血液学杂志》
CAS
2014年第1期82-85,共4页
International Journal of Blood Transfusion and Hematology
基金
国家自然科学基金课题(30971281),江苏省“六大高峰”人才课题(2012WSW035)
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