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动脉粥样硬化中炎性反应与内质网应激的相互作用 被引量：15

Interactions between inflammatory response and endoplasmic reticulum stress in atherosclerosis
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摘要 炎性反应和内质网应激均是动脉粥样硬化发生和发展过程中的重要事件。炎性反应可通过多条途径诱发内质网应激,而内质网应激在疾病的不同阶段可抑制或者促进炎性反应。 Inflammatory response and endoplasmic reticulum stress （ERS） are significant events in the process of atherosclerosis （AS）. Inflammatory response may induce ERS through several pathways, and ERS in turn may ei- ther enhance or reduce inflammatory response, according to what stage the atheroselerosis is in.
作者 项荣 严经纬 范亮亮 黄皓 夏昆
机构地区 中南大学生命科学学院细胞生物学系 中南大学医学遗传学国家重点实验室
出处 《基础医学与临床》 CSCD 北大核心 2014年第2期253-256,共4页 Basic and Clinical Medicine
基金 国家自然科学基金(30800476) 湖南省自然科学基金(11JJ3036)
关键词 炎性反应 内质网应激 动脉粥样硬化 inflammatory response endoplasmic reticulum stress atherosclerosis
分类号 R543.5 [医药卫生—心血管疾病]
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  • 1Wei L, Liu Y, Kaneto H, et al. JNK regulates serotonin- mediated proliferation and migration of pulmonary artery smooth muscle cells [ J ]. Am J Physiol Lung Cell Mol Phys- iol, 2010, 298:863 - 869.
  • 2Chen C, Khismatullin DB. Synergistic effect of histamine and TNF-α on monocyte adhesion to vascular endothelial cells[ J]. Inflammation, 2013, 36:309 - 319.
  • 3Khan MI, Pichna BA, Shi Y, et al. Evidence supporting a role for endoplasmic reticulum stress in the development of atherosclerosis in a hyperglycaemic mouse model [ J ]. An- tioxid Redox Signal, 2009, 11:2289 - 2298.
  • 4Kedi X, Ming Y, Yongping W, et al. Free cholesterol o- verloading induced smooth muscle cells death and activated both ER-and mitochondrial-dependent death pathway [ J ]. Atherosclerosis, 2009, 207 : 123 - 130.
  • 5Niculeseu IS, Sanda GM, Sima AV. HDL inhibit endo- plasmic reticulum stress by stimulating apoE and CETP se- cretion from lipid-loaded macrophages [ J ]. Biochem Bio- phys Res Commun, 2013, 434 : 173 - 178.
  • 6Mallavia B, Recio C, Oguiza A, et al. Peptide Inhibitor of NF-KB Translocation Ameliorates Experimental Atheroscle- rosis[J]. Am J Pathol, 2013, 182:1910 - 1921.
  • 7Kamari Y, Shaish A, Shemesh S, et al. Reduced athero-sclerosis and inflammatory cytokines in apolipoprotein-E-de- ficient mice lacking bone marrow-derived interleukin-lot [ J ]. Biochem Biophys Res Commun, 2011, 405: 197 - 203.
  • 8Haubner F, Leyh M, Ohmann E, et al. Effects of external radiation in a co-culture model of endothelial cells and adi- pose-derived stem cells[J]. Radiat Oncol, 2013, 8:66.
  • 9Fotis L, Agrogiannis G, Vlachos IS, et al. Intercellular ad- hesion molecule (ICAM) -1 and vascular cell adhesion mol- ecule (VCAM)-I at the early stages of atherosclerosis in a rat model[J]. In Vivo, 2012, 26:243-250.
  • 10Gargalovic PS, Gharavi NM, Clark M J, et al. The unfol- ded protein response is an important regulator of inflamma- tory genes in endothelial cells [ J ]. Arterioscler Thromb Vasc Biol, 2006, 26:2490 - 2496.

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基础医学与临床
2014年 第2期

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