睡眠K复合波的功能及其模型

The function and model of sleep K-complex

睡眠K复合波(K-complex,KC)是人脑非快速眼动睡眠脑电图上的最大成分。关于其功能一直存在分歧,一种观点认为KC是脑对内部或外部刺激的觉醒反应,另一种观点认为KC是维持睡眠的保护性反应。本文在阐述这两种观点之后,结合文献,提出KC的功能模型。根据模型,KC的产生主要依据脑内3种节律状态(睡眠周期、中枢振荡和皮质振荡)。结合睡眠信息评估中枢对刺激重要性的评估结果,KC的产生分别伴随完全觉醒、有唤醒征兆、无唤醒征兆3种不同的反应。最后得出KC是在刺激作用下的脑状态的反映。

K-complex （KC） is a major component of electroencephalography （EEG） in human brain during non-rapid eye movement sleep, and there has long been a debate on its function. Some researchers consider that KC represents a sign o~ arousal response of brain to internal or external stimuli, and others suggest that it is a protective response to sustain sleep. In this article we put forward a functional model of KC based on the above two views and related literatures. According to our model, KC arises from three kinds of brain rhythms （sleep cyclic, central oscillation, and cortical oscillation）. Based on the results of stimulus significance assessed by sleep-information assessment center, the generation of KC is related to three different responses-total arousal, sign of being awakened, and no sign of being awakened. In conclusion, KC is a reflection of cerebral state responsive to stimuli.