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雌激素受体影响泌乳素瘤发生的作用途径 被引量：2

Pathways of estrogen receptors participate in prolactinomas genesis
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摘要 腺垂体通过分泌激素和细胞可逆性改变来对内外环境中的信息做出反应，但可逆的细胞功能性改变可能发展为增生、分化，甚至是腺瘤。垂体腺瘤约占颅内新生物的10％～25％，
作者 朱孔江 杨辉
机构地区 第三军医大学新桥医院神经外科
出处 《局解手术学杂志》 2014年第1期84-86,共3页 Journal of Regional Anatomy and Operative Surgery
基金 国家自然科学基金(81071043)
关键词 雌激素受体 垂体腺瘤 泌乳素瘤
分类号 R651.1 [医药卫生—外科学] R584 [医药卫生—内分泌]
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参考文献12

  • 1Dworakowska D, Grossman AB. The pathophysiology of pituitary adeno- mas[ J]. Best Pratt Res Clin Endocrinol Metab, 2009,23 ( 5 ) : 525 - 541.
  • 2Bjornstrom L, Sjoberg M. Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes [ J ]. Mol Endocrino1,2005,19 (4) : 833 - 842.
  • 3Burdman JA,Pauni M,Heredia Sereno GM, et al. Estrogen receptors in human pituitary tumors[ J ]. Horm Metab Res,2008,40 (8) :524 -527.
  • 4Couse JF, Yates MM, Walker VR, et al. Characterization of the hypotha- lamic-pituitary-gonadal axis in estrogen receptor (ER) Null mice re- veals hypergonadism and endocrine sex reversal in females lacking ERol but not ERβ [ J ]. Mol Endocrino1,2003,17 (6) :1039 - 1053.
  • 5Ben Jonathan N,Chen S,Dunckley JA,et al. Estrogen receptor-α medi- ates the epidermal growth factor-stimulated prolactin expression and re- lease in lactotrophs [ J ]. Endocrinology, 2009,150 ( 2 ) :795 - 802.
  • 6Carroll JS, Liu XS, Brodsky AS, et al. Chromosome-wide mapping of es- trogen receptor binding reveals long-range regulation requiring the fork- head protein FoxA1 [ J ]. Cell,2005,122 ( 1 ) :33 - 43.
  • 7Adamson AD, Friedrichsen S, Semprini S, et al. Human prolactin gene promoter regulation by estrogen:convergence with tmnor necrosis factor- α signaling [ J ]. Endocrinology ,2008,149 ( 2 ) :687 - 694.
  • 8Lv H, Li C, Gui S, et al. Effects of estrogen receptor antagonist on bio- logical behavior and expression of growth factors in the prolactinoma MMQ cell line[J].J Neurooncol,2011,102(2) :237 -245.
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同被引文献28

  • 1Colao A. Pituitary tumours : the prolactinoma [ J ]. Best Pract ResClin Endocrinol Metab,2009,23(5) :575-596.
  • 2Kasantikul V,Shuan逆hoti S. Pituitary adenomas: immunohisto-chemical: study of 90 cases [ J ]. J Med Assoc Thai, 1990,73?9) ;514-521.
  • 3Berezin M, Shimon I,Hadani M. Prolactinoma in 53 men:clinical characteristics and modes of treatment ( maleprolactinoma) [ J] . J Endocrinol Invest ,1995 ,18(6) :436-441.
  • 4Colao A,Samo AD,Cappabianca P,et al. Gender differences inthe prevalence, clinical features and response to cabergoline inhyperprolactinemia [ J ] . Eur J Endocrinol, 2003,148 ( 3 );325-331.
  • 5Delgrange E, Trouillas J, Maiter D, et ai. Sex-related differencein the growth of prolactinomas : a clinical and proliferation markerstudy[ J]. J Clin Endocrinol Metab, 1997 ,82(7) :2102-2107.
  • 6Ippersiel W, Misson N, Donckier JE. Dramatic shrinkage of agiant prolactinoma in a male patient under medical management[J]. Acta Clin Belg,2012,67(2) ;140-141.
  • 7Lv H, Li C, Gui S,et al. Effects of estrogen receptor antagoniston biological behavior and expression of growth factors in theprolactinoma MMQ cell line[ J]. J Neurooncol,2011,102 (2):237-245.
  • 8Lv H, Li C, Gui S, et al. Expression of estrogen receptor alphaand growth factors in human prolactinoma and its correlation withclinical features and gender [ J ]. J Endocrinol Invest,2012,35(2):174-180.
  • 9Oh MC, Aghi MK, Dopamine agonist-resistant prolactinomas[J]. J Neurosurg,2011,114(5) : 1369-1379.
  • 10Nishioka H,Haraoka J,Akada K. Growth potential ofprolactinomas in men: is it really different from women? [ J].Surg Neurol,2003,59(5) :386-391.

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局解手术学杂志
2014年 第1期

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