放疗联合肝动脉化疗栓塞治疗原发性巨块型肝癌

目的：观察介入治疗联合放疗治疗原发性巨块型肝癌的临床疗效及毒副作用。方法：对60例患者行介入治疗12周期，随后行三维适形放疗。结果：治疗后完全缓解（CR）10例，部分缓解（PR）22例，无变化[NC）13例，1，2，3年存活率分别为89．7％、63．3％和23．1％。治疗后部分患者出现消化道副作用，经处理后能完成治疗。结论：介入化疗联合放疗能提高原发性巨块型肝癌的临床疗效，延长生存期，提高生活质量，且毒副作用可耐受。

Objective：To evaluated the treatment efficence and side effectts of interventonal chemotherapy with radiotherapy for the treatment of huge liv- er cancer. Methods：60 patients with huge liver cancer were treated with interventionaland radiotherapy. Results .. The effective rate（CR--PR）was 52.5%, and the survival rate of 1,2,3 years were 89.7 %, 63.3 %, 23.1 %, The main side effects and major toxicity of radiotherapy and chemotherapy were tolerated. Con- clusions Intervenitonal therapy with radiotherapy can significantly raise the effective rate, survival rate.