阿曲库铵与琥珀胆碱在无抽搐电休克（MECT）治疗中的应用比较

The application of atracurium Compare with suxamethonium in moden Non-convulsively electuoconvulsive therapy（MECT）

目的：探讨阿曲库胺与琥，自胆碱在无抽搐电休克治疗（MECT）中的应用比较。方法：选择18—60岁，ASAI-Ⅱ级，无截瘫、烧伤、过敏史、高血钾等器质性疾病的精神分裂症患者。随机分为阿曲库铵组（A组），阿曲库铵、新斯的明组（B组），琥珀胆碱组（C组），分别观察注药后肌松药起效时间、MECT治疗后呼吸恢复时间、呼吸恢复情况、病人完全清醒时间。结果与A组、B组相比较，C组病人肌松药起效时间、呼吸恢复时间，呼吸恢复情况快、短、好（P〈0．05）。B纽呼吸恢复时间较A纽快短（P〈0．05），肌松起效时间、呼吸恢复情况差异无统计学意义（P〉0．05）。三组病人完全清醒时间差异无统计学意义（P〉0．05）。结论：在无琥珀胆碱情况下，阿曲库铵与新斯的明合用不失为一种可行的MECT治疗方法。

Objective To compare the effect of both atracurium and suxamethonium in moden non convulsively electuoconvulsive therapy（MECT）. Meth- od Sixth mental patients aged from eighting to sixty, ASA I-II except for paraplegia, fire burn,allergy, hyperkalemia and other organic diseases were ran- domly divided into 3 groups： atracurium group （group A, n ： 20）,atracurium compound with neostigmine group （group B, n = 20）and suxamethonium group （group C, n =20）. Muscle relaxation onset time,breathing recovery time, recovery feeling and awake time were observed respectively. Result Muscle relaxation onset time, breathing recovery time, recovery feeling and awake time in group C were shorter and better than that in group A and group B （P〈0.05）. Breathing recovery time in group B was shorter than that in group A（P〈0.05）. Muscle relaxation onset time and recovery feeling in group B have no statistical difference than that in group A. Awake time among three groups have no significance statistical difference. Conclusion Atracurium com- pound with neostigmine is a good method in moden non convulsively electuoeonvulsive therapy if there has no Auxamethonium.