抗生素骨水泥在治疗慢性骨髓炎中的运用

Cement impregnated with antibiotics in treatment of chronic osteomyelitis

目的：探讨手工配制的抗生素骨水泥在治疗慢性骨髓炎上的有效性。方法：2008年11月到2012年11月，采用清创后，植入手工配制的抗生素骨水泥治疗了15例慢性骨髓炎患者，其中男性10例，女性5例；年龄23~55岁，平均37岁；骨髓炎发生部位：胫腓骨10例，股骨1例，尺挠骨2例，跟骨2例。结果：15例患者均临床治愈，无复发。15例患者随访12~24个月，平均15．2个月。结论：抗生素骨水泥治疗慢性骨髓炎可以取得较好的临床效果。

Obiective： To observe the effects of cement impregnated with antibiotics in treatment of chronic osteomyelitis. Methods： From November 2008 to November 2012, fifteen patients were treated by using debridementand and implanting with cement impregnated with antibiotics. There were 10 males and 5 females with an average age of 37 years （range,23 to 55 years）, osteomyelitis occurred in tibia in 8 cases, in radius and ulna in 2 cases,in femur in 1 case and calcaneus in 2 cases. Results： All the patients were followed up for 15.2（12 to 24）nlonths on average. All patients were cured, no recurrence was found . Conclusion Treatment of using debridementand and implanting with cement impregnated with antibiotics is an effective treatmentfor chronic osteomy- elitis.