呼气末正压对中枢性呼吸衰竭患者中心静脉压和平均动脉压的影响

Impact of Positive End-Expiratory Pressure on Central Venous Pressure and Mean Arterial Pressure in Patients with Central Respiratory Failure

目的探讨呼气末正压(PEEP)对中枢性呼吸衰竭患者中心静脉压(CVP)和平均动脉压(MAP)的影响。方法 40例中枢性呼吸衰竭患者均予同步间隙指令通气(SIMV),随机设定PEEP水平为0、3、6、9、12、15 cmH2O;记录患者CVP和MAP的变化。结果 CVP水平与PEEP设定值呈正相关关系(r=0.520,P=0.000)。但MAP水平与PEEP无线性相关。结论 PEEP对中枢性呼吸衰竭患者CVP有影响,每1 cmH2O的PEEP可使CVP检测值提高0.36 cmH2O,而对MAP无影响。

Objective To evaluate the impact of positive end-expiratory pressure （ PEEP ） on central venous pressure（CVP） and mean arterial pressure （MAP） in patients with central respiratory failure .Methods Forty patients with central respiratory failure were enrolled in the study .They were ventilated in the mode of synchronized intermittent mandatory ventilation （SIMV）,and six levels of PEEP （0,3,6,9,12,15 cmH2 O） were randomly chosen for all patients . The changes of their CVP and MAP were recorded .Results The CVP levels presented a positive correlation with the levels of PEEP（r=0.520,P=0.000）.But the values of MAP showed no linear correlation with the levels of PEEP . Conclusion PEEP has effects on CVP in patients with central respiratory failure ,approximately 0.36 cmH2 O of CVP elevation for 1 cmH2 O of PEEP added ,but has no effects on MAP .