低氧血症与OSAHS患者嗜睡的关系分析

Relationship between oxygen desaturation and daytime sleepiness in patients with obstructive sleep apnea hyponea syndrome

目的分析阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者低氧血症与白天嗜睡的关系。方法选取我院就诊的150例OSAHS患者为研究对象,根据嗜睡评分进行分组,比较嗜睡组与非嗜睡组的一般情况及夜间多导睡眠监测参数,并将各数据参数进行相关性分析。结果嗜睡组与非嗜睡组相比,嗜睡评分、睡眠呼吸暂停通气指数、氧减指数显著高于非嗜睡组(P<0.05),最低血氧饱和度显著低于非嗜睡组(P<0.05)。多元回归提示日间嗜睡评分仅与氧减指数相关。结论 OSAHS患者日间嗜睡与氧减指数密切相关,夜间低氧血症是OSAHS患者出现日间嗜睡的主要原因。

Objective To evaluate the relationship between oxygen desaturation and daytime sleepiness in patients with obstructive sleep apnea hyponea syndrome. polysomnography and the Epworth Sleepiness Scale（ESS） Methods 150 patients with OSAHS were evaluated by Then they were divided into two groups according to ESS scores. The correlation among the related indexes were analyzed. Results The scores of ESS Scale, AHI and nocturnal oxygen saturation index were obviously higher in the drowsiness group than in the non - drowsiness group （ P 〈 0.05）, and the lowest oxygen saturation was lower in the drowsiness group than in the non - drowsiness group （ P 〈 0.05）. Multiple stepwise regression showed that ESS was correlated with nocturnal oxygen saturation index. Conclu- sion ESS is closely correlated with nocturnal oxygen saturation in OSAHS patients, and oxygen desaturation can be a major determinant of excessive daytime sleepiness in OSAHS patients.