维生素C在新陈代谢中的生理功能

Physiological Function of Vitamin C in Metabolism

维生素C不仅通过直接清除活性氧簇还通过间接维持其他抗氧化剂的还原态在生物体内起着非常重要的抗氧化作用,而且在更多其他方面也起着非常重要的作用。本文从维生素C的抗氧化作用、作为双加氧酶的共基质所起的作用、维生素C基因表达上所起的的作用以及维生素C在脂类氧化和DNA损伤中的作用做了综述,希望人们以更加全面的观点来看待维生素C。

Vitamin C has powerful antioxidant function both directly via scavenging of reactive oxygen species and indirectly through regeneration of other antioxidant. While, simultaneously, its function involves in many more other fields. We introduced the remarkable function of vitamin C as a co-substrate of many important dioxygenases, as well as the intriguing function of vitamin C in gene expression, and finally, the pro-oxidant function of vitamin C in lipids and DNA damage to argue for a comprehensive perspective about vitamin C.