BiPAP预防慢性阻塞性肺疾病伴呼吸衰竭患者并发上消化道出血的效果

The effect of BiPAP in preventing patients with chronic obstructive pulmonary disease with respiratory failure concurred with upper gastrointestinal hemorrhage

目的评价双水平气道正压无创通气(BiPAP)预防慢性阻塞性肺疾病伴呼吸衰竭患者并发上消化道出血的效果。方法回顾性分析2007年2月至2011年10月收治的慢性阻塞性肺疾病伴Ⅱ型呼吸衰竭73例患者的临床资料,将使用BiPAP的患者41例作为观察组,拒绝使用BiPAP的32例患者作为对照组,观察上消化道出血的发生情况。结果观察组上消化道出血发生率为4.88%(2/41),与对照组[发生率为31.25%(10/32)]比较,差异有统计学意义(χ2=5.31,P<0.05)。结论 BiPAP对慢性阻塞性肺疾病伴呼吸衰竭患者并发上消化道出血有一定的干预作用,是一种有效、简便、无创而实用的治疗方法。

Objective To evaluate the effect of noninvasive bi-level positive pressure ventilation （BiPAP） in preventing the patients with chronic obstructive pulmonary disease （COPD） with respiratory failure concurred with upper gastrointestinal hemorrhage. Methods Retrospective analysis was conducted on the clinical data of 73 cases with COPD and respiratory failure enrolled in the hospital from February 2007 to October 2011.41 patients with BiPAP for treatment were taken as observation group, while the other 32 patients without BiPAP were taken as control group. The occurrence of the upper gastrointestinal hemorrhage in the two groups were observed. Results The occurrence rate of upper gastrointestinal hemorrhage in the observation group and the control group was 4.88% （2/41） and 31.25% （10/32） respectively ,and the difference between the two groups had statistical sig- nificance 0（2=5.31 ,P〈0.05）. Conclusion BiPAP has certain intervention effect to patients with COPD and respiratory failure concurred with upper gastrointestinal hemorrhage, and it is an effective, simple, non-invasive and practical method.