间苯三酚在老年人结肠镜检查中的应用效果

Application effect of phloroglucinol in colonscopy for the elderly

目的探讨间苯三酚在老年人结肠镜检查中的应用效果。方法选取2012年1月～2013年7月于本院进行结肠镜检查的患者198例．随机分为间苯三酚组100例和山莨菪碱组98例。间苯三酚组检查前10min肌内注射间苯三酚40mg，山莨菪碱组检查前10min肌内注射山莨菪碱10mg，观察两组插镜至回盲部的成功率、患者对疼痛的耐受程度；到达回盲部所需时间以及不良反应发生率。结果两组的达盲成功率比较，差异无统计学意义（P〉O．05），问苯三酚组插镜到达回盲部的时间为（10．4±5．O）min，短于山莨菪碱组的（15．7±7．O）min（P〈O．05）；两组疼痛耐受率和不耐受率比较，差异有统计学意义（P〈0．01）；两组患者均发生眩晕、低血压和心悸，但间苯三酚组的不良反应发生率低于山莨菪碱组（P〈O．01）。结论结肠镜检查中应用间苯三酚可以显著提高插镜至回盲部的成功率和减少达盲时间、降低患者的疼痛程度和不良反应发生率，更有利于老年患者进行消化系统疾病的诊断，值得临床推广应用。

Objective To explore the application effect of phloroglucinol in colonscopy for the elderly. Methods 198 patients underwent colonscopy were randomly divided into the phloroglucinol group （n=100） and the anisodamine group （n--98） in our hospital from January 2012 to July 2013.The phlorogtucinol group was given 40 mg phloroglucinol of in- tramuscular injection before l0 min examination,while the the anisodamine group was given 10mg anisodamine of intra- muscular injection before 10 min examination,success rate of inserting lens into ileocecus,tolerance degree of patients to pain,and time of inserting lens to ileocecus and adverse effects .occurrence rate of the two groups were observed. Results There was no statistical difference of success rate of inserting lens into ileocecus in the two groups （P〉0.05）,the time inserting lens to ileocecus in the phloroglucinol group [（10.4＋5.0）min] was shorter than that in the anisodamine group [（15.7_＋7.0）min] （P〈0.05）;there was a statistical difference of tolerance and intolerance degree in patients to pain of the two groups （P〈0.01）.Both groups have vertigo,hypotension and palpitation,but occurrence rate of adverse reactions in the phloroglucinol group was lower than that in the anisodamine group （P〈0.01）. Conclusion Application of phloroglu- cinol in colonscopy can obviously improve success rate of inserting lens to ileocecus and shorten the time of inserting lens to ileocecus,and lower the pain degree of patients and occurrence rate of adverse reactions.It＇s more beneficial to diagnosis of digestive system diseases of the elderly and worthy of being popularized in clinical work.