细菌内毒素检测在ICU病区感染性疾病患者中的应用价值

The application value of detection of bacterial endotoxin in patients with infectious disease in ICU ward

目的探讨细菌内毒素检测在ICU病区感染性疾病患者中的应用价值。方法回顾性分析16例细菌培养为G-杆菌感染患者(G-杆菌感染组)和20例细菌培养为非G-杆菌感染患者(非G-杆菌感染组)的血液内毒素检测结果。结果 G-杆菌感染组的血液内毒素检测结果为(4.987±10.609)EU/ml,非G-杆菌感染组为(0.043±0.052)EU/ml,两组比较,差异有统计学意义(P<0.05)。结论在ICU病区,细菌内毒素升高与G-杆菌感染有关,对感染性患者先进行内毒素检测有利于临床早期诊断和治疗,为临床治疗提供理论依据,具有很高的临床意义。

Objective To explore application value of detection of bacterial endotoxin in patients with infectious dis- ease in ICU ward. Methods The test results of 16 patients with G-bacillus infection of bacteria] culture （the G-bacillus infection group） and 20 patients with non-G-bacillus infection of bacterial culture （the non-G-bacillus infection group） were retrospectively analyzed. Results The test result of blood endotoxin in the G-bacillus infection group was （4.987± 10.609）EU/ml,while in the non-G-bacillus infection group,it was （0.043±O.052）EU/ml,and there was a statistical differ- ence between the two groups （P〈0.05）. Conclusion In ICU ward,the increasing of bacterial endotoxin is associated with G-bacillus infection.The test of bacterial endotoxin in infectious patients is useful for the early clinical diagnosis and treatment,and it provides the theoretical basis for clinical treatments,It has important clinical significance.