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小肠克罗恩病60例治疗分析 被引量:1

Treatment analysis of 60 patients with small bowel Crohn disease
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摘要 目的 探讨小肠克罗恩病的临床特征及诊治经验.方法 回顾性分析2006年1月~2013年1月复旦大学附属华山医院静安分院收治的小肠克罗恩病患者的一般资料、临床表现、辅助检查、治疗等相关临床资料.结果 本研究共纳入60例小肠克罗恩病患者,男女比例2.53∶1,年轻患者多见,慢性起病;临床表现以腹痛腹泻为主,结肠镜及小肠钡灌肠是主要的检查手段;内科治疗后症状多能改善,外科治疗多针对穿孔、出血、梗阻等并发症.结论 小肠克罗恩病临床表现多样,易漏诊误诊,应结合症状、影像资料及内镜检查结果进行综合判断. Objective To investigate the clinical characteristics, the experience of diagnosis and treatment of small in- testinal Crohn disease. Methods The general data, clinical manifestation, auxiliary examination and treatment of pa- tients with small intestinal Crohn disease admitted in Jing'an Branch, Huashan Hospital Affiliated to Fudan University from January 2006 to January 2013 were retrospectively reviewed. Results 60 patients had been enrolled, ratio of male to female was 2.53:1, more common in younger patients and chronic onset. The main symptoms were abdominal pain and diarrhea. Colonoscopy and small intestinal barium enema were the main means of checking. The symptoms of pa- tients were under control with medical treatment, and patients accepted surgery when gastrointestinal tract perforation, bowel obstruction and perforation happened. Conclusion Small bowel Crohn disease may cause diversity of clinical manifestations. Diagnosis of small bowel Crohn disease needs a combined course that integrates with all valuable clini- cal evidences and clues.
作者 顾而立
出处 《中国医药导报》 CAS 2014年第2期50-52,共3页 China Medical Herald
基金 上海市卫生局科研课题(编号20124237)
关键词 克罗恩病 小肠 回顾性研究 诊断 治疗 Crohn disease Small bowel Retrospective studies Diagnosis Treatment
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参考文献23

  • 1Wilkins T,Jarvis K,Patel J. Diagnosis and management of Crohn's disease [J]. Am Fam Physician,2011,84(12) : 1365- 1375.
  • 2Zheng JJ,Zhu XS,Huangfu Z,et al. Crohn's disease in China's Mainland: a systematic analysis of 50 years of re- search [J]. Chin J Dig Dis,2005,6(4) : 175-181.
  • 3Rocehi A, Benchimol EI,Bernstein CN,et al. Inflammatory bowel disease : a Canadian burden of illness review [J]. Can J Gastroenterol, 2012,26 ( 11 ) : 811-817.
  • 4Caprilli R,Gassull MA,Eseher JC,et al. European evidence based consensus on the diagnosis and management of Crohn's disease : special situations [J]. Gut, 2006,55 (Suppl 1 ) : 36- 58.
  • 5中华医学会消化病学分会炎症性肠病协作组,欧阳钦,胡品津,钱家鸣,郑家驹,胡仁伟.对我国炎症性肠病诊断治疗规范的共识意见(2007年,济南)[J].中华消化杂志,2007,27(8):545-550. 被引量:1022
  • 6胡仁伟,欧阳钦,陈曦,常玉英,白爱平,王瑞华,张虎.近15年我国炎症性肠病文献分析[J].胃肠病学,2007,12(2):74-77. 被引量:77
  • 7Kappelman MD,Rifas-Shiman SL, Kleinman K, et al. The prevalence and geographic distribution of Crohn's disease and ulcerative colitis in the United States [J]. Clin Gas- troenterol Hepatol, 2007,5 (12) : 1424-1429.
  • 8张绍衡,智发朝,白杨,徐智民,姜泊,张亚历,陈烨.小肠克罗恩病54例临床特征分析[J].现代消化及介入诊疗,2010,15(4):205-207. 被引量:5
  • 9李亚红,刘军英,张欣,方莹,李汀,韩英,吴开春.流行病学调查探讨炎症性肠病的危险因素[J].胃肠病学和肝病学杂志,2007,16(4):381-383. 被引量:12
  • 10Noguchi E, Homma Y, Kang X,et al. A Crohn's disease-as- sociated NOD2 mutation suppresses transcription of hu- man ILl0 by inhibiting activity of the nuclear ribonucle- oprotein hnRNP-A1 [J]. Nat Immunol,2009,10(5) :471- 479.

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同被引文献13

  • 1欧阳钦,Rakesh Tandon,KL Goh,潘国宗,KM Fock,Claudio Fiocchi,SK Lam,萧树东,张虎,梁红亮,王玉芳.亚太地区炎症性肠病处理共识意见(一)[J].胃肠病学,2006,11(4):233-238. 被引量:123
  • 2欧阳钦,胡品津,钱家鸣,郑家驹,胡仁伟.对我国炎症性肠病诊断治疗规范的共识意见[J].胃肠病学,2007,12(8):488-495. 被引量:751
  • 3Podolsky DK.Inflammatory bowel disease[J].N Engl J Med,2002,347:417-429.
  • 4Delaney CP,Fazio VW.Crohn's disease of the small bowel[J].Surg Clin North Am,2001,81:137-158.
  • 5Oshitani N,Yukawa T,Yamagami H,et al.Evaluation of deep small bowel involvement by double-balloon enteroscopy in Crohn’s disease[J].Am J Gastroentero,2006,101:1484-1489.
  • 6Fireman Z,Mahajna E,Broide E,et al.Diagnosing small bowel Crohn’s disease with wireless capsule endoscopy[J].Gut,2003,52:390-392.
  • 7Rutgeerts P,Feagan BG,Lichtenstein GR,et al.Comparison of scheduled and episodic treatment strategies of infliximab in Crohn's disease[J].Gastroenterology,2004,126(2):402-413.
  • 8Stange EF,Travis SPL,Vermeire S,et al.European evidence based consensus on the diagnosis and management of Crohn’s disease:definitions and diagnosis[J].Gut,2006,55(suppl1):1-15.
  • 9Bar-Meir S.Review article:capsule endoscopy-are all small in-testinal lesions Crohn's disease?[J].Aliment Pharmacol,2006,24(Suppl3):19-21.
  • 10Minordi LM,Vecchioli A,Mirk P,et al.CT enterography with polyethylene glycol solution vs CT enteroclysis in small bowel disease[J].Br J Radiol,2011,84(998):112-119.

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