摘要
目的 探索早期亚低温治疗对心肺复苏后患者预后的影响.方法 回顾性分析浙江省金华市中心医院急诊科ICU自2008年1月-2013年1月心肺复苏患者的病历,评价早期亚低温治疗对患者神经功能恢复、住院生存率和出院总存活率及生活质量的影响.结果 ①亚低温组28 d生存率与存活出院率分别为20.8％和17.0％;非早期亚低温组均为8.0％.②复苏后第7天时,亚低温组格拉斯哥和神经功能评分分别为（9.1±2.3）分和（1.9±0.4）分,非亚低温组为（6.5±2.8）分和（3.5±0.6）分,两组比较差异有统计学意义（P＜0.05）.③出院后24周,亚低温组活动能力评分与生活质量评分为（73.3±10.6）分与（49.3±8.7）分,非亚低温组为（58.3±9.8）分和（34.3±6.8）分,两组比较差异有统计学意义（P＜ 0.05）.结论 心肺复苏后使用亚低温治疗可以促进神经功能的恢复,改善患者生活质量等远期预后.
Objective To explore the impact of early application of mild hypothermia on patients＇prognosis.Methods Patients＇ documentswho admitted to ICU in Jinhua Municipal Central Hospital from January 2008 to January 2013 were retrospectively analyzed.Their nerve function recovery,inpatient hospital discharge survival rate and overall survival rate as well as life quality after discharge were compared.Results ①Patients＇28th day survival rates and survival rates at discharge were 20.8% and 17.0% in mild hypothermia group; but as low as 8% in non-hypothermia group.②Glasgow coma scale score and nerve function scores were （9.1±2.3） scores and （1.9±0.4） scores in mild hypothermia group at 7th day,and （6.5±2.8） scores and （3.5±0.6） scores in hypothermia group,accordingly with statistically significant difference （P 〈 0.05）.③Discharged from hospital after 24 weeks,living ability score （MBI） and quality of life （QOL） score were （73.3±10.6） scores and （49.3±8.7） scores in formal group,but as low as （58.3±9.8） scores and （34.3±6.8） scores in latter group （P 〈 0.05）.Conclusion Utility of mild hypothermia after cardiopulmonary resuscitation can promote the recovery of neurological function and improve quality of life in patients with long-term prognosis.
出处
《中国医药导报》
CAS
2014年第2期72-75,共4页
China Medical Herald
基金
教育部"高等学校博士学科点专项科研基金"联合资助课题(编号200800260003)
关键词
心肺复苏
脑复苏
亚低温
神经功能状况
生存率
Cardiopulmonary resuscitation
Cerebral resuscitation
Mild hypothermia
Conditions of neurological function
Survival rate
