丙泊酚和七氟烷全麻对老年患者血流动力学影响的研究

To Research the Hemodynamic Effects of Propofol and Sevoflurane Anesthesia on Hemodynamics in Elderly Patients

目的观察丙泊酚和七氟烷全麻对老年患者血流动力学的影响。方法选择我院2010年1月—2013年10月收治的胃癌根治术患者32例,随机分为对照组(采用丙泊酚)和观察组(采用七氟烷),观察两组术后不同时间收缩压(SBP)、舒张压(DBP)、平均动脉压(MAP)和呼吸(HR)的变化。结果两组患者T0时SBP、DBP、MAP和HR间比较,差异无统计学意义(P>0.05);与T0比较,两组患者T1、T2、T3、T4和T5时SBP差异无统计学意义(P>0.05),两组患者T4时DBP和MAP升高,且差异具有统计学意义(P<0.05),两组患者T1和T2时HR降低且差异具有统计学意义(P<0.05)。T1、T2、T3、T4和T5时两组患者间SBP、DBP、MAP和HR比较差异无统计学意义(P>0.05)。结论丙泊酚和七氟烷均可维持老年患者术中血流动力学的稳定。

Objective To observe the hemodynamic effects of propofol and sevoflurane anesthesia to elderly pa- tients. Methods The 32 eligible cases of patients with gastric cancer surgery in our hospital from January 2010 to October 2013 were elected to the group. The patients in the group were randomly divided into control group （propofol） and observation group （sevoflurane） to be observed the changes of contraction pressure （ SBP）, diastolic blood pressure （ DBP）, the mean arterial pressure （MAP） and respiratory （HR） at different times. Results The difference of SBP, DBP, MAP and HR for the two goup was not statistically significant at To （P 〉 0. 05） ; Compared with TO, the difference of SBP for the two groups at T1 , T2, T3, T4 and T5 was not statistically significant （P 〉 0. 05 ） . But the DBP and MAP for the two groups at T4 increased, and the difference was statistically significant （ P 〈 0. 05 ） . At T, and T2, the two groups had lower HR and the difference was statistical- ly significant （P 〈0. 05） ; At TI, T2, T3, T4 and T5 the difference of SBP, DBP, MAP and HR for the two groups was not statistically significant （P 〉 0. 05） . Conclusion Propofol and sevoflurane may remain stable intraoperative hemodynamics in elderly patients.