生物降解聚合物—聚乳酸泡沫材料(D.L-PLA)的研制及物理机械性能检测

The Construction and Physical——mechanical Characterization of Polymer Foams of D.L-PLA

本研究以生物降解聚合物—聚乳酸 (D .L PLA)为原料 ,在测定材料分子量、筛选颗粒型氯化钠及轮廓制图的基础上 ,应用溶媒投放、颗粒沥滤技术制备了单片方形或圆形的D .L PLA多孔生物降解膜 ,并采用层压技术 ,将 2 3层D .L PLA多孔性膜状物加工成三维立体聚合物泡沫材料。随后 ,对加工的泡沫材料物理、机械性能进行了检测 ,通过对检测结果的分析表明 :采用层压技术可以研制、加工出均匀多孔、可用于细胞移植的支架材料。

This study was intended to construct biogradable polymer foam used in tissue engineering. The D.L PLA was supplied by chengdu institute of organic chemistry. Biogradable polymer membranes were prepared with a novel solvent casting particulate leaching technique, then, the constituent membranes with the proper order were laminated to produce three dimensional foams with continuous pore structure and morphology. Afterwards, the physical mechanical property of polymer foams were tested. The test results indicated that the lamination process did not change the physical mechanical property of the polymer membranes.