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紫杉醇与卡铂联合化疗治疗晚期复发或转移宫颈癌 被引量:2

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摘要 目的评价晚期宫颈癌患者应用紫杉醇联合卡铂化疗的临床疗效及联合应用的安全性。方法对局部复发或远处转移的子宫颈癌患者36例,应用紫杉醇联合卡铂进行化疗,疗程结束后观察疗效和近期的毒副作用。结果总有效率为36.1%(其中CR1例、PR12例、NC10例、PD4例),中位缓解时间6.9个月;毒性反应以骨髓抑制为主,Ⅲ-Ⅳ度白细胞下降为37.1%,Ⅲ-Ⅳ度血小板下降为25.9%,无严重并发症发生。结论紫杉醇联合卡铂是治疗晚期复发或转移宫颈癌的有效药物,两者联合应用有协同作用,有良好的疗效,毒性反应低,耐受性较好,能提高临床反应率。
出处 《河北医药》 CAS 2014年第1期82-83,共2页 Hebei Medical Journal
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