脑苷肌肽对新生儿缺氧缺血性脑病听力的影响

Influences of naoganjitai injection on hearing screening of hypoxic-ischemic encephalopathy

目的:观察脑苷肌肽对新生儿缺氧缺血性脑病(HIE)听力的影响。方法:67例HIE患儿在常规综合治疗基础上,加脑苷肌肽治疗,观察治疗前后听力的变化。结果:67例HIE患儿听力异常耳数发生率为(35.8%,48/134);治疗10天后,第2次筛查听力异常耳数发生率为(19.4%,26/134),第3次筛查听力异常耳数发生率为(9.7%,13/134),第4次筛查听力异常耳数发生率为(1.5%,2/134),治疗后听力筛查通过率与治疗前比较,差异有统计学意义(P<0.05)。结论:脑苷肌肽治疗HIE能够显著提高HIE患儿听力筛查通过率。

Objective To observe the influences of Naoganjitai injection on hearing screening of hypoxicischemic encephalopathy( HIE). Methods 67 cases neonates with HIE were treated by combined therapy and Naoganjitai injection. We examined the changes on hearing screening of babies before and after treatment. Results Abnormal hearing screening incidence rate of HIE neonates was 35. 8%. After 10 days,abnormal hearing screening incidence rate was 19. 4%. The third handicap of hearing; was 9. 7%,and the final examin handicap of hearing was 1. 5%. Conclusion Naoganjitai injection can improve hearing screening of HIE.