珠海市西部地区2010-2012年疑似预防接种异常反应监测分析

Surveillance and analysis of suspected abnormal reactions after vaccination in the western region of Zhuhai City in 2010-2012

目的分析珠海市西部地区2010-2012年疑似预防接种异常反应(AEFI)发生情况及监测系统运转情况,评价监测系统运转灵敏性及预防接种疫苗的安全性。方法通过疑似预防接种异常反应信息管理系统,收集整理珠海市西部地区2010-2012年报告的AEFI个案,采用描述性方法对相关指标进行分析。结果珠海市西部地区2010-2012年共报告AEFI个案103例,发生率为11.47/10万。AEFI个案以一般反应为主,共72例,占69.90%,异常反应27例,占26.21%,偶合症3例,占2.91%,心因性反应1例,占0.97%。结论 AEFI监测系统运转情况良好,预防接种服务质量和疫苗的安生性较高。

Objective To analyze the incidence of suspected adverse events following immunization （AEFI） and monitor the running status of surveillance system in the western region of Zhuhai City from 2010 to 2012 so as to evaluate the sensitivity of the system and the safety of vaccines. Methods We collected AEFI cases reported by information management system for sus- pected adverse events following immunization in the western region of Zhuhai City from 2010 to 2012, and the relevant indexes were analyzed using descriptive statistics. Results A total of 103 AEFI cases were reported in the western region of Zhuhai City in 2010- 2012, with the incidence rate of 11.47/100,000. Most of AEFI cases were general - response - oriented, ac- counting for 69.90% （72/103）. There were 27 cases with abnormal reactions （26.21% ）, 3 coincident cases （2.91% ）, and 1 case with psychogenic reaction （0.97 % ） reported. Conclusions The working condition of AEFI surveillance system in the western region of Zhuhai City in 2010 - 2012 was good, moreover, the quality of preventive inoculation service and the safety of vaccines were both high.