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Th17相关细胞因子检测在90例类风湿关节炎中的应用价值 被引量:4

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摘要 目的探讨Th17相关细胞因子白细胞介素-17(IL-17)和白细胞介素-23(IL-23)检测在类风湿关节炎中的应用价值。方法采用酶联免疫吸附试验测定所有研究对象的IL-17和IL-23的浓度,结果用中位数(四分位数间距)表示,并分析其与类风湿关节炎活动度及X线片Sharp评分的关系。结果类风湿关节炎患者血清IL-17和IL-23水平明显高于健康者水平(P<0.01);血清IL-17和IL-23水平与患者活动度呈正相关(P<0.05),与患者X线Sharp评分也呈正相关关系(P<0.01)。结论类风湿关节炎患者的IL-17和IL-23水平与患者的活动度有关。
作者 贺微微
出处 《检验医学与临床》 CAS 2014年第2期229-230,共2页 Laboratory Medicine and Clinic
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