期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

1型糖尿病与肠道病毒感染之间的关系 被引量：2

The relationship between type 1 diabetes and enterovirus infection
原文传递
导出
摘要 1型糖尿病的发病机制复杂.作为环境因素之一的感染因素,肠道病毒感染与1型糖尿病密切相关.肠道病毒感染易感个体后,通过直接感染和引起自身免疫反应两种方式损伤β细胞,从而导致胰岛功能损伤,胰岛素分泌障碍,临床出现糖尿病,最终导致胰岛功能衰竭. The pathogenesis of type 1 diabetes is complicated. The infection of enterovirus is closely related to this disease as one of the environmental factors. After susceptible individuals are infected by enterovirus,beta cells in pancreas islets are damaged in two ways, direct infection and autoimmune responses, then leading to the decrease of insulin secretion, clinical diabetes, finally resulting in functional failure of pancre- atic islet.
作者 晋兴楠(综述) 邹映雪(审校)
机构地区 天津市儿童医院呼吸二科
出处 《国际儿科学杂志》 2014年第1期36-38,共3页 International Journal of Pediatrics
关键词 肠道病毒感染 1型糖尿病 Enterovirus infection Type 1 diabetes
分类号 R512.5 [医药卫生—内科学]
  • 相关文献

参考文献8

二级参考文献174

  • 1徐宽枫,徐萍,张梅,覃又文,刘超.三种胰岛自身抗体联合检测对1型糖尿病早期诊断的意义[J].南京医科大学学报（自然科学版）,2006,26(8):623-626. 被引量：9
  • 2Brownsey RW, Boone AN, Elliott JE, et al. Regulation of acetyl-CoA carboxylase [J]. Biochem Soc Trans,2006,34(Pt 2):223-227.
  • 3Targonsky ED, Dai F, Koshkin V, et al. Alpha-lipoic acid regulates AMP- activated protein kinase and inhibits insulin secretion from beta cells [J]. Diabetologia,2006,49(7): 1587-1598.
  • 4Kusunoki J, Kanatani A, Moiler DE, et al. Modulation of fatty acid metabolism as a potential approach to the treatment of obesity and the metabolic syndrome [J]. Endocrine,2006,29(11):91-100.
  • 5Roepstorff C, Halberg N, Hillig T, et al. Malonyl-CoA and carnitine in regulation of fat oxidation in human skeletal muscle during exercise [J]. Am J Physiol Endoerinol Metab,2005,288(3):E133-E142.
  • 6Chen ZP, Stephens TJ, Murthy S, et al. Effect of exercise intensity on skeletal muscle AMPK signaling in humans [J]. Diabetes,2003,52(5): 2205-2212.
  • 7Simmons R K,Unwin N,Griffin S J.International Diabetes Federation:An update of the evidence concerning the prevention of type 2 diabetes[J].Diabetes Res Clin Pract,2010;87(2):143-149.
  • 8Daneman D.State of the world's children with diabetes[J].Pediatric Diabetes,2009;10(2):120-126.
  • 9Atkinson M A,Eisenbarth G S.Type 1 diabetes:new perspectives on disease pathogenesis and treatment[J].Lancet,2001;358(9277):221-229.
  • 10Staeva-Vieira T,Peakman M,von Herrath M.Translational mini-review series on type 1 diabetes:Immune-based therapeutic approaches for type 1 diabetes[J].Clin Exp Immuno,2007;148(1):17-31.

共引文献13

同被引文献28

  • 1Imagawa A, Hanafusa T, Miyagawa J, et al. A novel subtype of type 1 diabetes mellitus characterized by a rapid onset and an absence of diabe- tes-related antibodies[ J]. N Engl J Med ,2000,342(5 ) :301 - 307.
  • 2Kim MS,Kim C J, Ko CW, et al. Fulminant type 1 diabetes mellitus in Korean adolescents[J]. J Pediatr Endocrinol Metab,2011,24(9 -10): 679 - 681.
  • 3Kim HS, Lee TY, Kim EY,et al. Fulminant type 1 diabetes in a pregnant woman as an initial manifestation of the insulin autoimmune syndrome [J]. Diabet Med,2012,29(10) :1335 - 1338.
  • 4International Diabetes Federation. Global IDF/ISPAD guideline for dia- betes in childhood and adolescence [ EB/OL]. [ 2013 - 03 - 27]. ht- tp://www, idf. org/sites/defauh/files/Diabetes-in-Childhood-and-Ado- lescence-Guidelines, pdf.
  • 5Imagawa A, Hanafusa T, Uehigata Y, et al. Fulminant type 1 diabetes : a nationwide survey in Japan [ J ]. Diabetes Care, 2003,26 ( 8 ) : 2345 - 2352.
  • 6Cho YM, Kim JT, Ko KS, et al. Fulminant type 1 diabetes in Korea: high prevalence among patients with adult-onset type 1 diabetes[ J ]. Diabetologia ,2007,50 ( 11 ) :2276 - 2279.
  • 7Napartivaumnuay N, Suthornthepvarakul T, Deeroehanawong C. Fulmi- nant type I diabetes:the first ease report in Thailand[ J]. J Med Assoc Thai ,2013 96( Suppl 3 ) : S114 - 117.
  • 8Kim HJ, Kim HS, Hahm JR, et al. The first vietnamese patient with ful- minant type 1 diabetes mellitus [ J]. Intern Med, 2012,51 (17) : 2361 - 2363.
  • 9Lee I,Harrison LC,Colman PG. Fluminant type 1 diabetes in Australia in the absence of humoral and cellular immune response to pancreati- cislet autoantigens[ J]. Diabetes Res Clin Praet,2012,95 (1) :e4 -6.
  • 10Yamashita K,Sato Y,Seki K,ct al. Fulminant type 1 diabetes with ro- bust recovery of insulin secretion:a case report [ J ]. Diabetes Res Clin Pract,2013,100(2) :e34 -38.

引证文献2

二级引证文献15

国际儿科学杂志
2014年 第1期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部