摘要
目的探讨黄曲霉毒素B1对昆明鼠血氨浓度的影响。方法用黄曲霉毒素B1注射昆明鼠10周,每2周测定1次昆明鼠鼠血氨浓度。结果毒素组昆明鼠血氨浓度从40μmol/L上升到170μmol/L,同时毒素组的血氨浓度相对于对照组呈上升趋势。结论黄曲霉毒素B1可诱发昆明鼠高血氨,推测黄曲霉毒素B1会干扰尿素循环。
Objective To investigate the effect of aflatoxin B1 on blood ammonia in KM mouse. Methods KM mouse were injec- ted with aflatoxin Bl,and the blood ammonia was measured every two week,lasting 10 weeks. Results Aflatoxin B1 induced blood ammonia significantly higher than control group, and the blood ammonia rised from 40μmol/L to 170 μmol/L. Conclusion Hy- perammonemia of KM mouse induced by aflatoxin B1 indicates that aflatoxin B1 can interrupt the urea cycle.
出处
《国际检验医学杂志》
CAS
2014年第2期132-133,共2页
International Journal of Laboratory Medicine
