住院肿瘤患者HCV抗体检测结果分析

Analysis of HCV antibody detection in hospitalized tumor patients

目的了解肿瘤医院住院患者中丙型肝炎病毒(HCV)的感染状况。方法对本院2008年1月至2012年12月期间的住院患者用酶联免疫吸附法(ELISA)检测血清HCV抗体,筛选出HCV抗体阳性患者相关资料进行回顾性分析。结果从67 438例患者中检出HCV抗体阳性327例,其中40～59岁龄段的占53.21%,男女比例为1.11∶1.00,科室分布以肝胃病区为主,2011年检出率最低为4.24‰,2008年检出率最高为5.95‰,病种以肝癌最多,占23.28%。结论肿瘤患者丙肝抗体阳性率低于一般人群、年龄跨度大、科室分布广、肿瘤谱宽。因此,对患者术前、输血前和各种创伤侵袭性操作前应该对其进行HCV常规检查,以防止院内感染的发生。

Objective To investigate the HCV infection condition of patients in tumor hospital. Methods ELISA was used to detect the HCV antibody in the blood sera of inpatients in the tumor hospital during January 2008 to December 2012,and the infor- mation about the positive results were analyzed with retrospective analysis. Results 327 positive serums HCV antibody were found among 67 438 individuals, the patients with age between 40 and 59 years accounted for 53.21 ~//00, and male and female ratio was 1.11：1.00. Patients with HCV antibody were mainly found in hepatobiliary ~ gastrointestinal surgical department. The lowest de- tection rate was 4. 240/oo in 2011 and the highest detection rate was 5.95‰ in 2008. The main disease was liver cancer,accounted for 23.28‰. Conclusion The positive rate of anti-HCV in patients with tumors might be lower than normal crowd,and the distribution of department,age and tumor types are becoming wide. So all patients before surgery,blood transfusion and all kinds of traumatic or intrusion inspection should take HCV detection.