50名健康成人生长激素对胰岛素耐量试验反应性的影响因素

Influencing factors of growth hormone in response to insulin tolerance test in 50 healthy adults

胰岛素耐量试验（ITT）激发的生长激素（GH）峰值是诊断成人生长激素缺乏症的“金标准”。本研究探讨50名中国健康成人中ITT激发的GH峰值的受影响因素。结果显示血糖谷值或血糖下降幅度与GH峰值无相关性。在多元回归分析中，ITT激发的GH与体重指数呈负相关（P〈0．01），与年龄、性别和腹围无显著相关性。

The peak level of growth hormone （GH） stimulated by insulin tolerance test （ITT） is the ＂ gold standard＂ for diagnosis of growth hormone deficiency in adults. This study was aimed to explore the factors influencing GH response to IIT in 50 healthy adults. The results showed that the nadir or decreased amplitude of blood glucose was not related to GH peak level. In muhivariable analysis, the GH level stimulated by ITr was negatively associated with body mass index （P〈0.01 ）, but there was no any association with age, gender, and waist circumference.