摘要
目的探讨丙泊酚联合瑞芬太尼全凭静脉麻醉患者全麻苏醒期间维持小剂量瑞芬太尼靶控输注对苏醒拔管质量的影响。方法择期脊柱侧弯后路矫形手术患者40例,随机分为对照组(全麻苏醒期间停用所有药物,n=20)和瑞芬太尼组(全麻苏醒期间维持瑞芬太尼小剂量靶控输注,n=20)。记录两组患者苏醒时间、拔管时间,并观察苏醒拔管质量评分。结果对照组患者苏醒时间为(12.76±3.56)min,拔管时间为(13.98±4.06)min;瑞芬太尼组患者苏醒时间为(13.14±3.87)min,拔管时间为(14.21±4.77)min,组间比较无显著差异。但对照组患者苏醒拔管质量评分为1、2、3、4和5分的患者例数分别为1、10、5、3和1例;瑞芬太尼组患者苏醒拔管质量评分为1、2、3、4和5分的患者例数分别为5、12、3、0和0例,组间比较有显著差异(P<0.05)。结论丙泊酚联合瑞芬太尼全凭静脉麻醉全麻苏醒拔管期间维持小剂量瑞芬太尼靶控输注可以改善苏醒拔管质量,且不延长苏醒拔管时间。
Objective To explore whether maintaining low dose remifentanil target controlled infusion（TCI）during emergence from general anesthesia can improve the quality of recovery profiles for the patients under total intrave-nous anesthesia with propofol and remifentanil. Methods Forty elective scoliosis surgical patients were randomized into two groups：control group（n = 20,all anesthetic drugs paused during emergence）and remifentanil group（n = 20,maintaining low dose remifentanil target controlled infusion while propofol infusion paused during emer-gence）. Awake time,tracheal extubation time and quality score of recovery status were recorded. Results Awake time and tracheal extubation time were（12. 76 ± 3. 56）min and（13. 98 ± 4. 06）min respectively in control group, while it were（13. 14 ± 3. 87）min and（14. 21 ± 4. 77）min respectively in remifentanil group. There was no signifi-cant difference of awake and tracheal extubation time between two groups. However,the patient number with quali-ty score of recovery status 1 /2 /3 /4 /5 in control group were 1 /10 /5 /3 /1 respectively,while it were 5 /12 /3 /0 /0 respectively in remifentanil group（P 〈0. 05）. Conclusions Maintaining low dose remifentanil target controlled infusion during emergence from general anesthesia can improve recovery quality and does not prolong awake time and tracheal extubation time for the patients under total intravenous anesthesia with propofol and remifentanil.
出处
《基础医学与临床》
CSCD
北大核心
2014年第1期109-112,共4页
Basic and Clinical Medicine
关键词
瑞芬太尼
靶控输注
拔管
恢复
remifentanil
target controlled infusion
extubation
recovery
