超声二维斑点追踪评价系统性红斑狼疮患者左室收缩功能

Evaluation of left ventricular systolic function in patients with systemic lupus erythematosus using two-dimensional speckle tracking technique

目的:应用超声二维斑点追踪技术检测系统性红斑狼疮(SLE)患者的左室纵向收缩期峰值应变(S)和应变率(Sr),探讨其评价SLE患者左室纵向收缩功能的临床应用价值。方法:选择30例SLE患者(SLE组)和32例正常人(对照组),分别进行超声心动图检查,获取心尖四腔、两腔和心尖长轴二维超声切面,应用超声斑点追踪技术在以上切面分别测量总体和各节段纵向收缩期峰值S和Sr。结果:SLE组Tei指数大于对照组(P<0.001);SLE组左室总体和各节段心肌纵向收缩期峰值S和Sr均小于对照组(P<0.05)。结论:SLE左室纵向总体及局部收缩功能减低,超声斑点追踪技术可早期评价SLE患者左室纵向收缩功能。

Objective： To assess the left ventricular systolic function using the longitudinal peak strain （S） and strain rate （Sr） with two-dimensional（2D） speckle tracking technique and evaluate its clinical value in patients with systemic lupus erythematosus （SLE）. Methods： Thirty SLE patients and 32 control subjects underwent the examination of echocardiography. 2D images were recorded in apical four chamber, two chamber and apical long axis view from the left ventricle. The global peak S and Sr and the peak S and Sr of segments were obtained in the above views using 2D speckle tracking technique. Results： The Tel index was increased in SLE patients （P〈0.001）. The global peak S and Sr and the peak S and Sr of segments were decreased in SLE patients （P〈0.05）. Conclusions： The global and regional left ventricular longitudinal systolic function is weak- ened in patients with SLE. 2D Speckle tracking technique is an accurate way for assessing the left ventricular systolic function.