糖尿病、糖尿病的治疗与心血管病（I）

Diabetes, anti-diabetic therapies and cardiovascular diseases （ [ ）

美国心脏联合会（AHA）1999年发表声明提出“糖尿病就是心血管病”的论点，引起了心血管和内分泌糖尿病领域学者们的高度关注。围绕糖尿病和心血管病的相关研究层出不穷，结论也莫衷一是。糖尿病患者是心血管病的高危人群，约有近2／3的糖尿病患者死于心血管病，糖尿病患者其心血管死亡是非糖尿病患者的2～3倍。有关糖尿病和冠心病的关系，有很多研究证据，也有很不相同的研究结果，本文综合具有代表性的临床试验研究，从高血糖与心血管事件、糖尿病是心血管病的等危症、糖尿病不是心血管病的等危症3个方面讨论糖尿病和心血管疾病的关系。

American Heart Association issued a statement in 1999 which put forward a point of view that ＂diabetes is a cardiovascular disease＂, which made experts in cardiology and endocrinology pay more attention to the relationship between the two diseases. Then, studies on diabetes mellitus and cardiovascular diseases emerged one after another, but there was no consensus finally achieved in their conclusions. Diabetes is a cardiovascular risk factor. About 2/3 diabetic patients died of cardiovascular diseases, and the cardiovascular death of diabetic patients was 2-3 times higher than that of non-diabetic patients. About the relationship between diabetes and coronary heart diseases, there was a great deal of evidence, but the results of the studies were different. In this paper, we reviewed representative clinical trials, and discussed the relationship between diabetes and cardiovascular diseases in 3 aspects, that is, hyperglycemia and cardiovascular events, diabetes as cardiovascular risk equivalents, and diabetes is not a cardiovascular disease.